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Found 3 Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM50117368'
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50117368(4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazoli...)
Affinity DataIC50:  170nMAssay Description:Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50117368(4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazoli...)
Affinity DataIC50:  250nMAssay Description:Inhibition of wild type Platelet-derived growth factor receptor beta phosphorylation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50117368(4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazoli...)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed