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Found 2 Enz. Inhib. hit(s) with Target = 'Poly(ADP-ribose) glycohydrolase' and Ligand = 'BDBM50508416'
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50508416(CHEMBL4518815)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50508416(CHEMBL4518815)
Affinity DataIC50:  90nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed