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Found
1
Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM27700'
Target
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human))
Deltagen Research Laboratories
Ligand
BDBM27700
(3,5-dimethyl-4,5,7-triazatricyclo[7.4.0.0^{2,6}]tr...)
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Affinity Data
IC50: 2.20nM
pH: 8.0 T: 2°C
Assay Description:
To assess the inhibitory activity of novel inhibitors, the PARP-1 enzyme assay was carried out in reaction mixture consisting of Escherichia coli str...
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