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Found 2 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-1' and Ligand = 'BDBM209932'
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM209932(2-[(2R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant PARP5a (E1023 to T1327 amino acids) incubated for 4 hrs by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM209932(2-[(2R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to PARP5a (unknown origin) assessed as apparent dissociation constantMore data for this Ligand-Target Pair
In DepthDetails PubMed