Found 5 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-2' and Ligand = 'BDBM50294835' TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Naples
Curated by ChEMBL
University Of Naples
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of full length human N-terminal GST-tagged TNKS2 ADP-ART catalytic domain (1001 to 1327 residues) using histone H2A as substrate incubated...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Naples
Curated by ChEMBL
University Of Naples
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of N-terminal His6-tagged human TNKS2 (946 to 1162 amino acid residues) after 60 mins by autoparsylation assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Naples
Curated by ChEMBL
University Of Naples
Curated by ChEMBL
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Naples
Curated by ChEMBL
University Of Naples
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Activity of N-terminus hexaHis-tagged human TNSK2 expressed in Escherichia coli BL21 (DE3) cells using biotinylated NAD+ as substrate after 90 mins b...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Naples
Curated by ChEMBL
University Of Naples
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Activity of N-terminus hexaHis-tagged human TNSK2 expressed in Escherichia coli BL21 (DE3) cells using biotinylated NAD+ as substrate after 90 mins b...More data for this Ligand-Target Pair
