Found 3 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50241262'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Pharmaceutical Sciences
Curated by ChEMBL
Institute Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of lipoxygenase 5 (unknown origin) product formation from endogenous substrate in Calcium and ionophore-stimulated polymorphonuclear leuko...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Pharmaceutical Sciences
Curated by ChEMBL
Institute Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 3.56E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in insect cells assessed as decrease in production of 5-HPETE and 5-HETE using arachidonic acid as su...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Pharmaceutical Sciences
Curated by ChEMBL
Institute Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 3.56E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in insect cells assessed as decrease in production of 5-HPETE and 5-HETE using arachidonic acid as su...More data for this Ligand-Target Pair