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Found 1 Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM50272760'
TargetPresenilin-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50272760(CHEMBL4126570)
Affinity DataIC50:  730nMAssay Description:Modulation of gamma secretase in human H4 cells expressing human wild type APP assessed as inhibition of amyloid beta 42 production after 22 hrs by e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed