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Found 9 Enz. Inhib. hit(s) with Target = 'Prokineticin receptor 1' and Ligand = 'BDBM121202'
TargetProkineticin receptor 1(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121202(US8722896, (+)-(2S)-2-Methyl-3-(indol-4- ylmethyla...)
Affinity DataKi:  2.38nM ΔG°:  -51.2kJ/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProkineticin receptor 1(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121202(US8722896, (+)-(2S)-2-Methyl-3-(indol-4- ylmethyla...)
Affinity DataKi:  4.08nM ΔG°:  -49.8kJ/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProkineticin receptor 1(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121202(US8722896, (+)-(2S)-2-Methyl-3-(indol-4- ylmethyla...)
Affinity DataKi:  4.24nM ΔG°:  -49.7kJ/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProkineticin receptor 1(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121202(US8722896, (+)-(2S)-2-Methyl-3-(indol-4- ylmethyla...)
Affinity DataKi:  7.18nM ΔG°:  -48.4kJ/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProkineticin receptor 1(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121202(US8722896, (+)-(2S)-2-Methyl-3-(indol-4- ylmethyla...)
Affinity DataKi:  10.7nM ΔG°:  -47.3kJ/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProkineticin receptor 1(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121202(US8722896, (+)-(2S)-2-Methyl-3-(indol-4- ylmethyla...)
Affinity DataKi:  11.4nM ΔG°:  -47.2kJ/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProkineticin receptor 1(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121202(US8722896, (+)-(2S)-2-Methyl-3-(indol-4- ylmethyla...)
Affinity DataKi:  14.9nM ΔG°:  -46.5kJ/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProkineticin receptor 1(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121202(US8722896, (+)-(2S)-2-Methyl-3-(indol-4- ylmethyla...)
Affinity DataKi:  18.1nM ΔG°:  -46.0kJ/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProkineticin receptor 1(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121202(US8722896, (+)-(2S)-2-Methyl-3-(indol-4- ylmethyla...)
Affinity DataKi:  240nM ΔG°:  -39.3kJ/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent