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Found 4 Enz. Inhib. hit(s) with Target = 'Prostaglandin D2 receptor 2' and Ligand = 'BDBM50296846'
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296846(2-(1-(4-fluoro-3-methoxyphenylsulfonyl)-2-methyl-1...)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296846(2-(1-(4-fluoro-3-methoxyphenylsulfonyl)-2-methyl-1...)
Affinity DataIC50:  18nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296846(2-(1-(4-fluoro-3-methoxyphenylsulfonyl)-2-methyl-1...)
Affinity DataIC50:  91nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296846(2-(1-(4-fluoro-3-methoxyphenylsulfonyl)-2-methyl-1...)
Affinity DataIC50:  156nMAssay Description:Antagonist activity against CRTh2 receptor in human whole blood assessed as eosinophil shape changeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed