Affinity DataIC50: 4nMAssay Description:Displacement of [3H]PGD2 from recombinant human CRTH2 receptor expressed in HEK293 cell membranes after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK293 cells assessed as inhibition of PGD2-induced calcium flux after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK293 cells assessed as inhibition of PGD2/forskolin-induced intracellular cAMP production ...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]PGD2 from recombinant human CRTH2 receptor expressed in HEK293 cell membranes after 90 mins by scintillation counting analysis in...More data for this Ligand-Target Pair
Affinity DataIC50: 275nMAssay Description:Antagonist activity at CRTH2 receptor in human eosinophils assessed as inhibition of PGD2-induced cell shape change incubated for 1 hr prior to PGD2 ...More data for this Ligand-Target Pair