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Found 2 Enz. Inhib. hit(s) with Target = 'Prostaglandin E synthase' and Ligand = 'BDBM50435047'
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435047(CHEMBL2391299)
Affinity DataIC50:  3nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50435047(CHEMBL2391299)
Affinity DataIC50:  119nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed