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Found 3 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1' and Ligand = 'BDBM50289303'
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289303(5-(4-Methanesulfonyl-phenyl)-6-phenyl-3,5-dihydro-...)
Affinity DataIC50: >3.00E+4nMAssay Description:In vitro inhibition of the production of PGE-2 in arachidonic acid stimulated chinese hamster ovary (CHO) cellstransfected with human cyclooxygenase-...More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289303(5-(4-Methanesulfonyl-phenyl)-6-phenyl-3,5-dihydro-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human COX1 expressed in CHO cells assessed as reduction in arachidonic acid-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289303(5-(4-Methanesulfonyl-phenyl)-6-phenyl-3,5-dihydro-...)
Affinity DataIC50: >5.00E+4nMAssay Description:In vitro inhibition of the production of PGE-2 in arachidonic acid stimulated chinese hamster ovary (CHO) cellstransfected with human cyclooxygenase-...More data for this Ligand-Target Pair
In DepthDetails Article