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Found 5 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50029613'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50029613(1-Methoxy-4-(2-(4-(methanesulfonyl)phenyl)cyclopen...)
Affinity DataIC50:  0.5nMAssay Description:In vitro inhibition of prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50029613(1-Methoxy-4-(2-(4-(methanesulfonyl)phenyl)cyclopen...)
Affinity DataIC50:  5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50029613(1-Methoxy-4-(2-(4-(methanesulfonyl)phenyl)cyclopen...)
Affinity DataIC50:  5nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50029613(1-Methoxy-4-(2-(4-(methanesulfonyl)phenyl)cyclopen...)
Affinity DataIC50:  5.01nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50029613(1-Methoxy-4-(2-(4-(methanesulfonyl)phenyl)cyclopen...)
Affinity DataIC50:  7nMAssay Description:Inhibition of COX2 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed