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Found
1
Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-8' and Ligand = 'BDBM388331'
Target
Proteasome subunit beta type-8
(Homo sapiens (Human))
Merck Patent
US Patent
Ligand
BDBM388331
(US10294246, Compound No. 28)
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Affinity Data
IC50: <50nM
Assay Description:
Measurement of LMP7 inhibition is performed in 384 well format based on fluorescence intensity assay.Purified human immunoproteasome (0.25 nM) and se...
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Target Info
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Reactome pathway
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B.MOAD
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Ligand Info
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US Patent
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