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Found 1 Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 5' and Ligand = 'BDBM50581711'
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50581711(CHEMBL5078692)
Affinity DataIC50:  17nMAssay Description:Inhibition of PRMT5 in human HCT116-MTAP null cells assessed as reduction in symmetric dimethylation of arginine using SAM as substrate incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed