Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50126045'
LigandPNGBDBM50126045(4-[3-(4-Chloro-phenyl)-1-hydroxy-1-(3-methyl-3H-im...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50126045(4-[3-(4-Chloro-phenyl)-1-hydroxy-1-(3-methyl-3H-im...)
Affinity DataEC50:  9.5nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed