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Found 3 Enz. Inhib. hit(s) with Target = 'Protein kinase C beta type' and Ligand = 'BDBM50162996'
TargetProtein kinase C beta type(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162996(3-[1-(3-Dimethylamino-propyl)-1H-indazol-3-yl]-4-[...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human Protein kinase C beta 2 using [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162996(3-[1-(3-Dimethylamino-propyl)-1H-indazol-3-yl]-4-[...)
Affinity DataIC50:  24nMAssay Description:Inhibition of IL-8 release by HEK293 cells expressing PKC-beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162996(3-[1-(3-Dimethylamino-propyl)-1H-indazol-3-yl]-4-[...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human Protein kinase C beta 1 using [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed