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Found 1 Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase receptor Ret' and Ligand = 'BDBM4627'
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM4627(5-[(6,7-dimethoxyquinazolin-4-yl)amino]-4-fluoro-2...)
Affinity DataIC50:  0.75nMAssay Description:Inhibition of human RET cytoplasmic domain (658 to 1114 residues) expressed in baculovirus system preincubated for 15 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed