Found 7 Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase receptor Ret' and Ligand = 'BDBM60665' TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Rigel
Curated by ChEMBL
Rigel
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of Ret by biochemical assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Rigel
Curated by ChEMBL
Rigel
Curated by ChEMBL
Affinity DataKd: 2.20nMAssay Description:Binding constant for RET(V804L) kinase domainMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Rigel
Curated by ChEMBL
Rigel
Curated by ChEMBL
Affinity DataKd: 4.10nMAssay Description:Binding constant for RET(M918T) kinase domainMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Rigel
Curated by ChEMBL
Rigel
Curated by ChEMBL
Affinity DataKd: 3.10nMAssay Description:Binding constant for RET(V804L) kinase domainMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Rigel
Curated by ChEMBL
Rigel
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Inhibition of Ret in human SK-N-SH cellsMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Rigel
Curated by ChEMBL
Rigel
Curated by ChEMBL
Affinity DataEC50: 36nMAssay Description:Inhibition of Ret in human SK-M-MC cells assessed as assessed as phosphorylation after 1 hr incubationMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Rigel
Curated by ChEMBL
Rigel
Curated by ChEMBL
Affinity DataKd: 4.10nMAssay Description:Binding constant for RET kinase domainMore data for this Ligand-Target Pair
