Found 12 Enz. Inhib. hit(s) with Target = 'Purine nucleoside phosphorylase' and Ligand = 'BDBM50214707'
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of calf PNP in presence of 0.025 mM phosphateMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of human erythrocyte PNP assessed as inhibition of 7-methylguanosine phosphorolysis after 50 mins by spectrophotometry in presence of 0.02...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of calf spleen PNP assessed as inhibition of 7-methylguanosine phosphorolysis after 50 mins by spectrophotometry in presence of 0.025 mM i...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of human PNP in presence of 0.025 mM phosphateMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataKi: 4.40nMAssay Description:Inhibition of calf spleen PNP assessed as inhibition of 7-methylguanosine phosphorolysis after 50 mins by spectrophotometry in presence of 1 mM inorg...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataKi: 6.90nMAssay Description:Inhibition of bovine PNP using 7-methylguanosine as substrate by spectrophotometric based coupled assayMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataKi: 8.10nMAssay Description:Inhibition of human erythrocyte PNP assessed as inhibition of 7-methylguanosine phosphorolysis after 50 mins by spectrophotometry in presence of 1 mM...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataIC50: 10.2nMAssay Description:Inhibition of calf spleen PNP assessed as inhibition of 25 uM 7-methylguanosine phosphorolysis by spectrophotometry in presence of 1 mM inorganic pho...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataIC50: 10.2nMAssay Description:Inhibition of calf PNP in presence of 1 mM phosphateMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataIC50: 20.4nMAssay Description:Inhibition of human erythrocyte PNP assessed as inhibition of 25 uM 7-methylguanosine phosphorolysis by spectrophotometry in presence of 1 mM inorgan...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataIC50: 20.4nMAssay Description:Inhibition of human PNP in presence of 1 mM phosphateMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataKd: 0.100nMAssay Description:Binding affinity to calf recombinant PNP expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry/ fluorimetric titration analysi...More data for this Ligand-Target Pair