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Found 5 Enz. Inhib. hit(s) with Target = 'Purine nucleoside phosphorylase' and Ligand = 'BDBM50293088'
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Universit£

Curated by ChEMBL
LigandPNGBDBM50293088(7-((2R,3R,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)py...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of Plasmodium falciparum His-tagged PNP assessed as inhibitor constant for enzyme-inhibitor-substrate complex formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293088(7-((2R,3R,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)py...)
Affinity DataKi:  9nMAssay Description:Inhibition of human PNP assessed as inhibitor constant for enzyme-inhibitor-substrate complex formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293088(7-((2R,3R,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)py...)
Affinity DataKi:  12nMAssay Description:Inhibition of human PNP by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Universit£

Curated by ChEMBL
LigandPNGBDBM50293088(7-((2R,3R,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)py...)
Affinity DataKi:  18nMAssay Description:Inhibition of Plasmodium falciparum His-tagged PNP assessed as inhibitor constant for enzyme-inhibitor complex formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50293088(7-((2R,3R,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)py...)
Affinity DataKi:  32nMAssay Description:Inhibition of human PNP assessed as inhibitor constant for enzyme-inhibitor complex formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB