Found 10 Enz. Inhib. hit(s) with Target = 'Receptor tyrosine-protein kinase erbB-2' and Ligand = 'BDBM31340' TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Arromax Pharmatech
Curated by ChEMBL
Arromax Pharmatech
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant GST-tagged HER2 (unknown origin) (catalytic domain 675 to 1225) residues expressed in baculovirus-infected Sf9 cells assess...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Arromax Pharmatech
Curated by ChEMBL
Arromax Pharmatech
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of ERBB2 (unknown orgin)More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Arromax Pharmatech
Curated by ChEMBL
Arromax Pharmatech
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant HER2 (675 to 1255) (unknown origin) expressed in baculovirus infected Sf9 insect cells using poly-Glu-Tyr as substrate incu...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Arromax Pharmatech
Curated by ChEMBL
Arromax Pharmatech
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human GST-fused HER2 (675 to 1255 residues) assessed as phosphotyrosine formation using poly(Glu:Tyr, 4:1) as substrate and...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Arromax Pharmatech
Curated by ChEMBL
Arromax Pharmatech
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Arromax Pharmatech
Curated by ChEMBL
Arromax Pharmatech
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of ERBB2 (unknown orgin) by cell-based assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Arromax Pharmatech
Curated by ChEMBL
Arromax Pharmatech
Curated by ChEMBL
Affinity DataKd: 43nMAssay Description:Binding affinity to wild-type partial length human ERRB2 (K646 to V1225 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Arromax Pharmatech
Curated by ChEMBL
Arromax Pharmatech
Curated by ChEMBL
Affinity DataKd: 43nMAssay Description:Binding constant for ERBB2 kinase domainMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Arromax Pharmatech
Curated by ChEMBL
Arromax Pharmatech
Curated by ChEMBL
Affinity DataKd: 43nMAssay Description:Binding affinity to wild-type partial length human ERRB2 (K646 to V1225 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Arromax Pharmatech
Curated by ChEMBL
Arromax Pharmatech
Curated by ChEMBL
Affinity DataKd: 43nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
