Found 5 Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 1' and Ligand = 'BDBM356249' TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataKi: 9nMAssay Description:The ability of the receptor interacting protein kinase (RIPK1) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) is monitored using...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataKi: 28nMAssay Description:The ability of the receptor interacting protein kinase (RIPK1) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) is monitored using...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 500nMAssay Description:Test compounds were diluted in DMSO and 0.1 μL of solution was dispensed to each well of a 384-well white solid microplate. The assay buffer was...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 500nMAssay Description:Assay was performed in polystyrene low volume 384-well black plate, at Room Temperature (RT) in a final volume of 10.1 μl/well using 10 nM of GS...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:Fluorescent polarization binding assay was performed in polystyrene low volume 384-well black plate, at Room Temperature (RT) in a final volume of 10...More data for this Ligand-Target Pair
