Found 4 Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 1' and Ligand = 'BDBM50004205' TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataIC50: 208nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataIC50: 980nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataKd: 20nMAssay Description:Binding affinity to RIPK1 (unknown origin)More data for this Ligand-Target Pair
