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Found 4 Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM375952'
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375952(US10947243, Example 18 | US9914735, Example 18)
Affinity DataIC50:  1.34E+4nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375952(US10947243, Example 18 | US9914735, Example 18)
Affinity DataIC50:  1.34E+4nMAssay Description:Recombinant human Aurora B (amino acids 1-344, clone number DU1773, Molecular weight 40.2 kDa, University of Dundee) was expressed as a fusion protei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375952(US10947243, Example 18 | US9914735, Example 18)
Affinity DataIC50:  1.34E+4nMAssay Description:FLT3 is obtained from Invitrogen in 50 mM Tris (pH7.5); 100 mM NaCl; 0.05 mM EDTA, 0.05% NP-40, 2 mM DTT; 50% Glycerol # PV3182; Lot 286671; sequence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375952(US10947243, Example 18 | US9914735, Example 18)
Affinity DataIC50:  1.34E+4nMAssay Description:FLT3 is obtained from Invitrogen in 50 mM Tris (pH7.5); 100 mM NaCl; 0.05 mM EDTA, 0.05% NP-40, 2 mM DTT; 50% Glycerol # PV3182; Lot 286671; sequence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent