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Found 3 Enz. Inhib. hit(s) with Target = 'Renin' and Ligand = 'BDBM212580'
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM212580(US10155731, Example 271 | US9278944, 271)
Affinity DataIC50:  3.70nMAssay Description:A substrate of synthetic peptide (Nma-KHPFHLVIHK(Dnp)-NH2) and test compound were mixed, and fluorescence intensity was assayed using a fluorophotome...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM212580(US10155731, Example 271 | US9278944, 271)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM212580(US10155731, Example 271 | US9278944, 271)
Affinity DataIC50:  3.70nMAssay Description:A substrate of synthetic peptide (Nma-KHPFH LVIHK(Dnp)-NH2) and test compound were mixed, and fluorescence intensity was assayed using a fluorophotom...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent