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Found 4 Enz. Inhib. hit(s) with Target = 'Renin' and Ligand = 'BDBM50427564'
TargetRenin(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427564(CHEMBL2322611)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant human renin by fluorescence based FRET assayMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427564(CHEMBL2322611)
Affinity DataIC50:  170nMAssay Description:Inhibition of human recombinant renin expressed in CHO cells using RE(EDANS)IHPFHLVIHTK(Dabcyl)R as substrate incubated for 1 hr prior to substrate a...More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427564(CHEMBL2322611)
Affinity DataIC50:  300nMAssay Description:Inhibition of renin in human plasma using RE(EDANS)IHPFHLVIHTK(Dabcyl)R as substrate incubated for 1 hr prior to substrate addition measured after 2 ...More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427564(CHEMBL2322611)
Affinity DataIC50:  450nMAssay Description:Inhibition of human recombinant renin expressed in CHO cells using RE(EDANS)IHPFHLVIHTK(Dabcyl)R as substrate incubated for 1 hr prior to substrate a...More data for this Ligand-Target Pair