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Found 1 Enz. Inhib. hit(s) with Target = 'Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma' and Ligand = 'BDBM14394'
LigandPNGBDBM14394(5-(2-butoxy-5-acetylpyridin-3-yl)-3-ethyl-2-(pyrid...)
Affinity DataIC50:  183nMpH: 7.4 T: 2°CAssay Description:PDE5 or PDE6 catalytic activity was monitored by measuring the hydrolysis of [3H]-cGMP to [3H]-GMP using a scintillation proximity assay (SPA). [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed