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Found 8 Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50063002'
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University

Curated by ChEMBL
LigandPNGBDBM50063002(CHEMBL3398101)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 pre-incubated with compound before enzyme addition using poly(rA) template and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University

Curated by ChEMBL
LigandPNGBDBM50063002(CHEMBL3398101)
Affinity DataKi:  1.54E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant using radioactively-labeled [alpha-32P]ATP substrate and activated DNA as template-primer compl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University

Curated by ChEMBL
LigandPNGBDBM50063002(CHEMBL3398101)
Affinity DataKi:  1.59E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutant using radioactively-labeled [alpha-32P]ATP substrate and activated DNA as template-primer compl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University

Curated by ChEMBL
LigandPNGBDBM50063002(CHEMBL3398101)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase G190A mutant using radioactively-labeled [alpha-32P]ATP substrate and activated DNA as template-primer compl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University

Curated by ChEMBL
LigandPNGBDBM50063002(CHEMBL3398101)
Affinity DataKi:  6.33E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant using radioactively-labeled [alpha-32P]ATP substrate and activated DNA as template-primer compl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University

Curated by ChEMBL
LigandPNGBDBM50063002(CHEMBL3398101)
Affinity DataKi:  6.76E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase V106A mutant using radioactively-labeled [alpha-32P]ATP substrate and activated DNA as template-primer compl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University

Curated by ChEMBL
LigandPNGBDBM50063002(CHEMBL3398101)
Affinity DataKi:  6.99E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C mutant using radioactively-labeled [alpha-32P]ATP substrate and activated DNA as template-primer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University

Curated by ChEMBL
LigandPNGBDBM50063002(CHEMBL3398101)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 pre-incubated with compound before enzyme addition using poly(rA) template and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed