Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM163433'
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bioaxone Biosciences

US Patent
LigandPNGBDBM163433(BA-1049 | US11198680, Compound BA 1049 (R) | US968...)
Affinity DataIC50:  240nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bioaxone Biosciences

US Patent
LigandPNGBDBM163433(BA-1049 | US11198680, Compound BA 1049 (R) | US968...)
Affinity DataIC50:  340nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 15 uM. The hi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bioaxone Biosciences

US Patent
LigandPNGBDBM163433(BA-1049 | US11198680, Compound BA 1049 (R) | US968...)
Affinity DataIC50:  340nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 15 uM. The hi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Rattus norvegicus (Rat))
Bioaxone Biosciences

US Patent
LigandPNGBDBM163433(BA-1049 | US11198680, Compound BA 1049 (R) | US968...)
Affinity DataIC50:  940nMT: 2°CAssay Description:The inhibitor potency of BA-1049 (racemic mixture) and Fasudil (Calbiochem) were compared by fluorescent polarization assays performed using a Biomek...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Rattus norvegicus (Rat))
Bioaxone Biosciences

US Patent
LigandPNGBDBM163433(BA-1049 | US11198680, Compound BA 1049 (R) | US968...)
Affinity DataIC50:  1.60E+3nMT: 2°CAssay Description:The inhibitor potency of BA-1049 (racemic mixture) and Fasudil (Calbiochem) were compared by fluorescent polarization assays performed using a Biomek...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bioaxone Biosciences

US Patent
LigandPNGBDBM163433(BA-1049 | US11198680, Compound BA 1049 (R) | US968...)
Affinity DataKd:  160nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
In DepthDetails US Patent