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Found 1 Enz. Inhib. hit(s) with Target = 'Ribonucleoside-diphosphate reductase subunit M2' and Ligand = 'BDBM50198892'
TargetRibonucleoside-diphosphate reductase subunit M2(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50198892(3-AP | 3-aminopyridine-2-carboxaldehyde thiosemica...)
Affinity DataIC50:  185nMAssay Description:Inhibition of human RRM2 expressed in Escherichia coli BL21-codon plus(DE3) using [14C]-ADP as substrate after 3 mins by liquid scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed