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Found
1
Enz. Inhib. hit(s) with Target = 'SH2B adapter protein 2' and Ligand = 'BDBM484993'
Target
SH2B adapter protein 2
(Human)
Relay Therapeutics
US Patent
Ligand
BDBM484993
(US10934302, Example 244)
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Affinity Data
IC50: <50nM
Assay Description:
SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
B.MOAD
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Ligand Info
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Details
US Patent
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