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Found 2 Enz. Inhib. hit(s) with Target = 'Secreted frizzled-related protein 1' and Ligand = 'BDBM50308691'
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308691(5-(Phenylsulfonyl)-2-(trifluoromethyl)-N-(1-{[6-(t...)
Affinity DataIC50:  50nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308691(5-(Phenylsulfonyl)-2-(trifluoromethyl)-N-(1-{[6-(t...)
Affinity DataEC50:  140nMAssay Description:Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed