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Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk1' and Ligand = 'BDBM50204703'
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50204703(4-(6-((4-hydroxypiperidin-1-yl)methyl)-1,4-dihydro...)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant CHK1 assessed as human Cdc25C phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50204703(4-(6-((4-hydroxypiperidin-1-yl)methyl)-1,4-dihydro...)
Affinity DataEC50: >5.90E+4nMAssay Description:Antiproliferative activity against human SW620 cells by soft agar assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed