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Found 2 Enz. Inhib. hit(s) with Target = 'Signal peptide peptidase-like 2A' and Ligand = 'BDBM50263005'
TargetSignal peptide peptidase-like 2A(Homo sapiens)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50263005(CHEMBL4077336)
Affinity DataIC50:  225nMAssay Description:Inhibition of human SPPL2a expressed in HEK293 cells using GAL4-VP16 fusedTNFalpha (1 to 76)-NTF as substrate after 24 hrs by Bright-Glo luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal peptide peptidase-like 2A(Mus musculus)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50263005(CHEMBL4077336)
Affinity DataIC50:  496nMAssay Description:Inhibition of mouse SPPL2a in A20 cells assessed as CD74/p8 accumulation by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed