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Found 2 Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 3' and Ligand = 'BDBM50353447'
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353447(CHEMBL1829875 | US10196373, Compound 45M)
Affinity DataIC50:  6.74E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
The Governing Council of The University of Toronto

US Patent
LigandPNGBDBM50353447(CHEMBL1829875 | US10196373, Compound 45M)
Affinity DataIC50:  1.00E+5nMAssay Description:ChIP assay was performed using EZ ChIP Kit (Millipore, Billerica, Mass., USA) as per manufacturer's instruction. Briefly, after crosslinking with...More data for this Ligand-Target Pair
In DepthDetails US Patent