Found 44 Enz. Inhib. hit(s) with Target = 'Similar to alpha-tubulin isoform 1' and Ligand = 'BDBM50005480'
Affinity DataKi: 140nMAssay Description:Inhibition of [3H] colchicine binding to bovine brain tubulin incubated for 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Inhibition of bovine brain tubulin assessed as rate of assembly preincubated for 15 mins by turbidimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Tested for inhibition against tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of bovine brain tubulin polymerization (ITP).More data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of bovine brain tubulin polymerization preincubated for 15 mins followed by GTP addition and measured for 20 mins by turbidimetry-based sp...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Inhibition of bovine tubulin assembly after 15 mins by turbidimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 660nMAssay Description:Concentration inhibiting tubulin polymerization (ITP)More data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 960nMAssay Description:Inhibition of tubulin assembly in bovine brain homogenate assessed as reduction in turbidity increase preincubated for 15 mins followed by GTP additi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of bovine brain tubulin assemblyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration required against MAP-rich tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of bovine brain tubulin assemblyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of bovine brain tubulin assembly after 20 mins incubation by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization incubated for 20 mins in presence of GTPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization preincubated for 15 mins followed by GTP addition measured after 20 mins by spectrophotometric meth...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization preincubated for 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization by turbidimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of bovine brain tubulin assessed as extent of assembly preincubated for 15 mins by turbidimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:The compound was tested for the concentration to inhibit 50% of tubulin polymerization.More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 15 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization measured every 1 min for 60 mins by turbidimetry based microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization measured every 1 min for 60 mins by turbidimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of tubulin polymerization in bovine brain by tubulin assembly assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization incubated for 60 mins by microplate reader based turbidimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of bovine brain tubulin preincubated for 20 mins by turbidimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization measured every 30 sec for 30 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Ability to inhibit Tubulin polymerization in Bovine brainMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of tubulin polymerization reported as IC50More data for this Ligand-Target Pair
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of [3H] colchicine binding to bovine brain tubulin incubated for 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization measured every 30 secs for 30 mins by turbidimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of tubulin (10 uM) polymerization, after a 20 min incubation at 30 degrees CentigradeMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by turbidimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of tubulin polymerization with preincubation for 15 minutes at 37 degree Centigrade prior to addition of the GTP required for polymerizati...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Evaluated for the inhibition of tubulin polymerization without pre-incubationMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:The compound was evaluated for the anti-tubulin activity.More data for this Ligand-Target Pair
Affinity DataKd: 310nMAssay Description:Inhibition of [3H] colchicine binding to bovine brain tubulin incubated for 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair