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Found 3 Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 3' and Ligand = 'BDBM50058715'
TargetSodium/hydrogen exchanger 3(Oryctolagus cuniculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | ENIPORIDE | N-(5-Methane...)
Affinity DataIC50:  8nMAssay Description:Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 3(Oryctolagus cuniculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | ENIPORIDE | N-(5-Methane...)
Affinity DataIC50:  8nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | ENIPORIDE | N-(5-Methane...)
Affinity DataIC50: >3.00E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-3 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed