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Found 1 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 8 subunit alpha' and Ligand = 'BDBM621822'
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM621822((S)-N-((R or S)-(3- choro-4-fluoro- phenyl)(2-(1- ...)
Affinity DataIC50:  1.10nMAssay Description:Compounds were tested on human NaV1.8 and NaV1.5 channels stably expressed in human embryo kidney (HEK) 293 cells. Sodium current measurements on Qub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent