Found 6 Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent betaine transporter' and Ligand = 'BDBM50039246'
TargetSodium- and chloride-dependent betaine transporter(Mus musculus)
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of mouse mGAT2 expressed in HEK293 cells assessed as inhibition of [3H]GABA uptake after 3 mins incubation by TopCount microplate scintill...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataIC50: 7.17E+4nMAssay Description:Inhibition of human BGT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataIC50: 7.17E+4nMAssay Description:Inhibition of human BGT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of human GABA transporter (hBGT-1) activity.More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataIC50: 1.41E+5nMAssay Description:Inhibition of human BGT1 assessed as [3H]GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mus musculus)
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mouse BGT1 mediated [3]GABA uptake expressed in HEK293 cells after 3 mins by scintillation countingMore data for this Ligand-Target Pair