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Found 5 Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM141254'
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM141254(US8653100, 148 | US8653100, 151 | US8653100, 159 |...)
Affinity DataKi: <100nMpH: 7.5Assay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM141254(US8653100, 148 | US8653100, 151 | US8653100, 159 |...)
Affinity DataKi: <100nMpH: 7.5Assay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM141254(US8653100, 148 | US8653100, 151 | US8653100, 159 |...)
Affinity DataKi: <100nMpH: 7.5Assay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM141254(US8653100, 148 | US8653100, 151 | US8653100, 159 |...)
Affinity DataKi: <1.00E+4nMpH: 7.5Assay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM141254(US8653100, 148 | US8653100, 151 | US8653100, 159 |...)
Affinity DataKi: <1.00E+4nMpH: 7.5Assay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In DepthDetails US Patent