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Found 3 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM433673'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433673(US10562878, Compound 254 | US10562878, Compound 26...)
Affinity DataIC50: <1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433673(US10562878, Compound 254 | US10562878, Compound 26...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433673(US10562878, Compound 254 | US10562878, Compound 26...)
Affinity DataIC50:  100nMAssay Description:Quantification of dopamine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat striatum. The uptake of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent