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Found 8 Enz. Inhib. hit(s) with Target = 'Somatostatin receptor type 4' and Ligand = 'BDBM311911'
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM311911(US10166214, Example 47 | US10675268, Example 47 | ...)
Affinity DataKi:  39.9nMAssay Description:The displacement of the labeled ligand by the test compound leads to a decreased signal. For the binding experiments 200 μL of membrane homogena...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM311911(US10166214, Example 47 | US10675268, Example 47 | ...)
Affinity DataKi:  39.9nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM311911(US10166214, Example 47 | US10675268, Example 47 | ...)
Affinity DataKi:  39.9nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM311911(US10166214, Example 47 | US10675268, Example 47 | ...)
Affinity DataKi:  39.9nMAssay Description:The displacement of the labeled ligand by the test compound leads to a decreased signal. For the binding experiments 200 μL of membrane homogena...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM311911(US10166214, Example 47 | US10675268, Example 47 | ...)
Affinity DataKi:  39.9nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM311911(US10166214, Example 47 | US10675268, Example 47 | ...)
Affinity DataKi:  39.9nMAssay Description:The displacement of the labeled ligand by the test compound leads to a decreased signal. For the binding experiments 200 μL of membrane homogena...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM311911(US10166214, Example 47 | US10675268, Example 47 | ...)
Affinity DataEC50:  3.70nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM311911(US10166214, Example 47 | US10675268, Example 47 | ...)
Affinity DataEC50:  3.70nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
In DepthDetails US Patent