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Found 4 Enz. Inhib. hit(s) with Target = 'Sterol O-acyltransferase 2' and Ligand = 'BDBM50360305'
TargetSterol O-acyltransferase 2(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50360305(CHEMBL409855 | US9149492, Beauveriolide III)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of African green monkey SOAT2 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50360305(CHEMBL409855 | US9149492, Beauveriolide III)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of SOAT2 (unknown origin) expressed in CHO cells using [14C]oleic acid incubated for 6 hrsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSterol O-acyltransferase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50360305(CHEMBL409855 | US9149492, Beauveriolide III)
Affinity DataIC50: >2.00E+4nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSterol O-acyltransferase 2(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50360305(CHEMBL409855 | US9149492, Beauveriolide III)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed