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Found 4 Enz. Inhib. hit(s) with Target = 'Substance-P receptor' and Ligand = 'BDBM251918'
TargetSubstance-P receptor(Homo sapiens (Human))
Euroscreen

US Patent
LigandPNGBDBM251918(US10065961, Compound 17 | US10683295, Compound 17 ...)
Affinity DataKi:  6.06E+3nM ΔG°:  -29.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK1 receptor was evaluated in CHO recombinant cells which express the human NK1 receptor. Membrane...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSubstance-P receptor(Homo sapiens (Human))
Euroscreen

US Patent
LigandPNGBDBM251918(US10065961, Compound 17 | US10683295, Compound 17 ...)
Affinity DataKi:  6.06E+3nMAssay Description:NK1: The affinity of compounds of the invention for the NK1 receptor was evaluated in CHO recombinant cells which express the human NK1 receptor. Mem...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSubstance-P receptor(Homo sapiens (Human))
Euroscreen

US Patent
LigandPNGBDBM251918(US10065961, Compound 17 | US10683295, Compound 17 ...)
Affinity DataKi:  6.06E+3nMAssay Description:NK1: The following radioligand: [3H] substance P (PerkinElmer Cat#NET111520) was used in this assay. Binding assays were performed in a 50 mM Tris/5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSubstance-P receptor(Homo sapiens (Human))
Euroscreen

US Patent
LigandPNGBDBM251918(US10065961, Compound 17 | US10683295, Compound 17 ...)
Affinity DataKi:  6.06E+3nM ΔG°:  -29.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK1 receptor was evaluated in CHO recombinant cells which express the human NK1 receptor. Membrane...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent