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Found 2 Enz. Inhib. hit(s) with Target = 'Thioredoxin reductase 1, cytoplasmic' and Ligand = 'BDBM50462013'
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Nantong University

Curated by ChEMBL
LigandPNGBDBM50462013(CHEBI:8241 | Piplartine)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of TrxR in human BEL-7402/5-FU cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Nantong University

Curated by ChEMBL
LigandPNGBDBM50462013(CHEBI:8241 | Piplartine)
Affinity DataIC50:  4.59E+4nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed