Found 5 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily A member 1' and Ligand = 'BDBM50362753' TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Janssen Pharmaceutica
Curated by ChEMBL
Janssen Pharmaceutica
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of BITC-induced increase in intracellular calcium concentration by ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
University Of Ferrara
Curated by ChEMBL
University Of Ferrara
Curated by ChEMBL
Affinity DataIC50: 128nMAssay Description:Antagonist activity at human TRPA1 expressed in CHO cells assessed as inhibition of calcium influxMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
University Of Ferrara
Curated by ChEMBL
University Of Ferrara
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of 5H-dibenzo[b,e]azepine-10-carboxylic acid methyl ester-induced...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
University Of Ferrara
Curated by ChEMBL
University Of Ferrara
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at human TRPA1 expressed in human IMR90 cells assessed as inhibition of acrolein-induced calcium influx after 40 mins by fluoresc...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Janssen Pharmaceutica
Curated by ChEMBL
Janssen Pharmaceutica
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Antagonist activity at Sprague-Dawley rat TRPA1 expressed in rat DRG neurons assessed as inhibition of acrolein-induced calcium influx after 40 mins ...More data for this Ligand-Target Pair
