Found 4 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM50275762' TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Antagonist activity at recombinant rat TRPV1 expressed in HEK293 cells assessed as reduction in capsaicin-induced Ca2+ flux preincubated for 3 mins f...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Antagonist activity at recombinant human TRPV1 expressed in CHOK1 cells assessed as reduction in capsaicin-induced Ca2+ flux after 15 mins by fluo-4-...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:Antagonist activity at recombinant human TRPV1 expressed in CHOK1 cells assessed as reduction in temperature-induced Ca2+ flux after 15 mins at 45 de...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 8.70nMAssay Description:Antagonist activity at recombinant human TRPV1 expressed in CHOK1 cells assessed as reduction in low pH-induced Ca2+ flux after 15 mins by fluo-4-bas...More data for this Ligand-Target Pair
