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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM350150'
Target
Tyrosine-protein kinase BTK
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM350150
((1S,3R)-3-[8-amino-1-(4- {(1R)-1-hydroxy-1-[3- (tr...)
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Affinity Data
IC50: 178nM
Assay Description:
BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...
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Ligand Info
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