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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM412883'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Loxo Oncology

US Patent
LigandPNGBDBM412883(N-[[4-[4-amino-1-(4-hydroxycyclohexyl)pyrazolo[3,4...)
Affinity DataIC50:  0.400nMAssay Description:BTKWT binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. 2.5...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent